Rudi Cormane Lecture

Title: Immune signals in skin regeneration

Keynote speaker

Sabine Eming

Professor of Dermatology
Dermatology, University of Cologne, Germany

BIOGRAPHY

Dr. Sabine Eming is Professor of Dermatology at the University of Cologne, Germany. She studied Medicine at the University of Cologne, University of California San Diego and Harvard Medical School.

She received her MD and her training in Dermatology at the University of Cologne. She was research fellow at The Scripps Research Institute and Harvard Medical School. Dr. Eming’s research interests focus on basic mechanisms of how immune regulatory networks coordinate tissue regeneration post injury.

Her findings aim to improve the understanding and therapy of inflammatory and fibrotic skin pathologies associated with misregulated repair responses, autoimmune diseases including scleroderma, malignant growth and skin aging.

Top 5 selected publications

FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6Chigh Wound Macrophages from Damaged Tissue.

Injarabian L, Willenborg S, Welcker D, Sanin DE, Pasparakis M, Kashkar H, Eming SA. J Invest Dermatol. 2024 Jan;144(1):152-164.e7. doi: 10.1016/j.jid.2023.06.203.

 

A common framework of monocyte-derived macrophage activation.

Sanin DE, Ge Y, Marinkovic E, Kabat AM, Castoldi A, Caputa G, Grzes KM, Curtis JD, Thompson EA, Willenborg S, Dichtl S, Reinhardt S, Dahl A, Pearce EL, Eming SA, Gerbaulet A, Roers A, Murray PJ, Pearce EJ. Sci Immunol. 2022 Apr 15;7(70):eabl7482. doi: 10.1126/sciimmunol.abl7482.

 

Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing.

Willenborg S, Sanin DE, Jais A, Ding X, Ulas T, Nüchel J, Popović M, MacVicar T, Langer T, Schultze JL, Gerbaulet A, Roers A, Pearce EJ, Brüning JC, Trifunovic A, Eming SA. Cell Metab. 2021 Dec 7;33(12):2398-2414.e9. doi: 10.1016/j.cmet.2021.10.004.

 

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle.

Kim CS, Ding X, Allmeroth K, Biggs LC, Kolenc OI, L’Hoest N, Chacón-Martínez CA, Edlich-Muth C, Giavalisco P, Quinn KP, Denzel MS, Eming SA, Wickström SA. Cell Metab. 2020 Oct 6;32(4):629-642.e8. doi: 10.1016/j.cmet.2020.08.011.

 

Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation.

Ding X, Willenborg S, Bloch W, Wickström SA, Wagle P, Brodesser S, Roers A, Jais A, Brüning JC, Hall MN, Rüegg MA, Eming SA. J Allergy Clin Immunol. 2020 Jan;145(1):283-300.e8. doi: 10.1016/j.jaci.2019.07.033.